Mass-transfer based modeling to investigate iodine staining effects for enhanced contrast X-ray computed tomography

doi:10.1016/j.palwor.2018.10.004

IVPP-IR > 中科院古脊椎所（2000年以后）

	Mass-transfer based modeling to investigate iodine staining effects for enhanced contrast X-ray computed tomography
	Li, Zhi-Heng 1,2; Yan, Fei 3; Ketcham, Richard A.4; Colbert, Matthew W.4; Clarke, Julia A.4
	2019-12-01
发表期刊	PALAEOWORLD
ISSN	1871-174X
卷号	28 期号:4 页码:562-571
通讯作者	Li, Zhi-Heng(lizhiheng@ivpp.ac.cn)
摘要	Iodine staining combined with X-ray computed tomography (CT) has become a core approach in anatomy, offering three-dimensional and essentially non-destructive imaging of soft tissues. Although there have been rapid advances in methodologies and techniques, the mechanisms underlying diffusible iodine contrast-enhanced CT are not yet fully understood. The protocols for staining samples of differing sizes and tissue types have not yet been justified theoretically. Here we utilize mass transfer modeling to simulate iodine diffusion and predict iodine concentrations within distinct tissue types. We also undertake iodine staining experiments to visualize the detailed anatomy and contrast effects on whole-body avian specimens using different concentrations of iodine solution to compare with model simulation results. The simulations effectively explain most observed concentration changes in differently-sized samples over distinct iodine treatment durations. These results also provide insight into the mechanisms behind the efficacy of solution replenishment for enhancing staining effects. Both consistencies and inconsistencies between our simulation and experimental results regarding iodine concentration in tissues will inform further investigations to optimize iodine staining protocols. (C) 2018 Elsevier Ireland Ltd Elsevier B.V. and Nanjing Institute of Geology and Palaeontology, CAS. Published by Elsevier B.V. All rights reserved.
关键词	Computed tomography Iodine Contrast Staining Birds
DOI	10.1016/j.palwor.2018.10.004
关键词[WOS]	MICROCT IMAGES ; DICECT ; TOOL ; CT
收录类别	SCI
语种	英语
资助项目	Strategic Priority Research Program of the Chinese Academy of Sciences[XDA19050102] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDA 20070203] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDB26000000] ; One Hundred Talent Program of the Chinese Academy of Sciences ; NSFC[41772013] ; Gordon and Betty Moore Foundation[4498] ; NSF[EAR1258878]
项目资助者	Strategic Priority Research Program of the Chinese Academy of Sciences ; One Hundred Talent Program of the Chinese Academy of Sciences ; NSFC ; Gordon and Betty Moore Foundation ; NSF
WOS研究方向	Paleontology
WOS类目	Paleontology
WOS记录号	WOS:000499969100014
出版者	ELSEVIER
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://119.78.100.205/handle/311034/16787
专题	中科院古脊椎所（2000年以后）
通讯作者	Li, Zhi-Heng
作者单位	1.Chinese Acad Sci, Inst Vertebrate Paleontol & Paleoanthropol, Key Lab Vertebrate Evolut & Human Origins, Beijing 100044, Peoples R China 2.CAS Ctr Excellence Life & Paleoenvironm, Beijing 100044, Peoples R China 3.Rice Univ, Dept Civil & Environm Engn, Houston, TX USA 4.Univ Texas Austin, Dept Geol Sci, Austin, TX 78712 USA
推荐引用方式 GB/T 7714	Li, Zhi-Heng,Yan, Fei,Ketcham, Richard A.,et al. Mass-transfer based modeling to investigate iodine staining effects for enhanced contrast X-ray computed tomography[J]. PALAEOWORLD,2019,28(4):562-571.
APA	Li, Zhi-Heng,Yan, Fei,Ketcham, Richard A.,Colbert, Matthew W.,&Clarke, Julia A..(2019).Mass-transfer based modeling to investigate iodine staining effects for enhanced contrast X-ray computed tomography.PALAEOWORLD,28(4),562-571.
MLA	Li, Zhi-Heng,et al."Mass-transfer based modeling to investigate iodine staining effects for enhanced contrast X-ray computed tomography".PALAEOWORLD 28.4(2019):562-571.