The applications and potential prospects of paleogenomics in investigating the demographic changes and adaptive evolution of the giant panda

doi:10.1007/s11430-024-1598-x

IVPP-IR

	The applications and potential prospects of paleogenomics in investigating the demographic changes and adaptive evolution of the giant panda
	Li, Kexin 1,3; Chen, Zehui 1,2,3; Fu, Qiaomei1,2,3
	2025-07-01
发表期刊	SCIENCE CHINA-EARTH SCIENCES
ISSN	1674-7313
卷号	68 期号:7 页码:2061-2072
通讯作者	Chen, Zehui(chenzehui@ivpp.ac.cn) ; Fu, Qiaomei(fuqiaomei@ivpp.ac.cn)
摘要	The giant panda (Ailuropoda melanoleuca) is a rare species endemic to China, and also serves as a flagship species for global biodiversity conservation. Elucidating its evolutionary history is of great significance for conservation efforts. However, knowledge about the demographic changes and adaptive evolution of the giant panda remains limited. Paleogenomic research, with its broad temporal and geographic coverage, provides a novel perspective for addressing these questions. Given this, this study discusses three core topics related to the evolution of the giant panda. Firstly, we systematically consolidated the fossil records from the Late Miocene to the Holocene, along with their related studies, illustrating the impact of climatic and anthropogenic factors on the demographic history of the giant panda. In particular, climate change served as the primary driver of population fluctuations during the Pleistocene, leading to two episodes of population expansion and bottleneck. Additionally, human activities played a significant role in population divergence and demographic changes during the Holocene. Secondly, we also elucidated the adaptive process of the giant panda in terms of their highly specialized diet, highlighting long-term adaptation in morphology, genetics, and gut microbiota composition, which have led to its unique adaptive traits. Finally, the potential and significance of the paleogenomic studies in deepening our understanding of the demographic history and adaptive evolution of the giant panda were discussed. Meanwhile, this study demonstrated the potential of paleogenomic approaches for resolving species identification and obtaining individual-level information from fossil specimens, using ancient samples excavated from Baling in Shaanxi and Bamianshan in Hunan as case studies.
关键词	Giant panda Paleogenomics Demographic changes Adaptive evolution Species and individual identification
DOI	10.1007/s11430-024-1598-x
关键词[WOS]	BAMBOO-EATING GIANT ; DNA ; CHINA ; CAVE ; HISTORY ; ADAPTATION ; ADMIXTURE ; GENOMICS ; INSIGHTS ; PROVINCE
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[32100489] ; National Natural Science Foundation of China[41925009] ; National Natural Science Foundation of China[42262001] ; National Natural Science Foundation of China[42102001]
项目资助者	National Natural Science Foundation of China
WOS研究方向	Geology
WOS类目	Geosciences, Multidisciplinary
WOS记录号	WOS:001509395300001
出版者	SCIENCE PRESS
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.205/handle/311034/24630
专题	中国科学院古脊椎动物与古人类研究所
通讯作者	Chen, Zehui; Fu, Qiaomei
作者单位	1.Chinese Acad Sci, Inst Vertebrate Paleontol & Paleoanthropol, Key Lab Vertebrate Evolut & Human Origins, Beijing 100044, Peoples R China 2.State Adm Culture Heritage SACH, Key Sci Res Base Paleolith Human Evolut & Paleogen, Beijing 100044, Peoples R China 3.Univ Chinese Acad Sci, Coll Earth & Planetary Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Li, Kexin,Chen, Zehui,Fu, Qiaomei. The applications and potential prospects of paleogenomics in investigating the demographic changes and adaptive evolution of the giant panda[J]. SCIENCE CHINA-EARTH SCIENCES,2025,68(7):2061-2072.
APA	Li, Kexin,Chen, Zehui,&Fu, Qiaomei.(2025).The applications and potential prospects of paleogenomics in investigating the demographic changes and adaptive evolution of the giant panda.SCIENCE CHINA-EARTH SCIENCES,68(7),2061-2072.
MLA	Li, Kexin,et al."The applications and potential prospects of paleogenomics in investigating the demographic changes and adaptive evolution of the giant panda".SCIENCE CHINA-EARTH SCIENCES 68.7(2025):2061-2072.