Evo-Devo of amniote integuments and appendages

IVPP-IR > 中科院古脊椎所（2000年以后）

	Evo-Devo of amniote integuments and appendages
	Wu, P ; Hou, LH ; Plikus, M ; Hughes, M ; Scehnet, J ; Suksaweang, S ; Widelitz, RB ; Jiang, TX ; Chuong, CM ; Chuong, CM (reprint author), Univ So Calif, Keck Sch Med, Dept Pathol, HMR 315B,2011 Zonal Ave, Los Angeles, CA 90089 USA.
	2004
发表期刊	INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
ISSN	0214-6282
卷号	48 期号:2-3 页码:249-270
文章类型	Review
摘要	Integuments form the boundary between an organism and the environment. The evolution of novel developmental mechanisms in integuments and appendages allows animals to live in diverse ecological environments. Here we focus on amniotes. The major achievement for reptile skin is an adaptation to the land with the formation of a successful barrier. The stratum corneum enables this barrier to prevent water loss from the skin and allowed amphibian / reptile ancestors to go onto the land. Overlapping scales and production of beta-keratins provide strong protection. Epidermal invagination led to the formation of avian feather and mammalian hair follicles in the dermis. Both adopted a proximal - distal growth mode which maintains endothermy. Feathers form hierarchical branches which produce the vane that makes flight possible. Recent discoveries of feathered dinosaurs in China inspire new thinking on the origin of feathers. In the laboratory, epithelial - mesenchymal recombinations and molecular mis-expressions were carried out to test the plasticity of epithelial organ formation. We review the work on the transformation of scales into feathers, conversion between barbs and rachis and the production of "chicken teeth". In mammals, tilting the balance of the BMP pathway in K14 noggin transgenic mice alters the number, size and phenotypes of different ectodermal organs, making investigators rethink the distinction between morpho-regulation and pathological changes. Models on the evolution of feathers and hairs from reptile integuments are discussed. A hypothetical Evo-Devo space where diverse integument appendages can be placed according to complex phenotypes and novel developmental mechanisms is presented.; Integuments form the boundary between an organism and the environment. The evolution of novel developmental mechanisms in integuments and appendages allows animals to live in diverse ecological environments. Here we focus on amniotes. The major achievement for reptile skin is an adaptation to the land with the formation of a successful barrier. The stratum corneum enables this barrier to prevent water loss from the skin and allowed amphibian / reptile ancestors to go onto the land. Overlapping scales and production of beta-keratins provide strong protection. Epidermal invagination led to the formation of avian feather and mammalian hair follicles in the dermis. Both adopted a proximal - distal growth mode which maintains endothermy. Feathers form hierarchical branches which produce the vane that makes flight possible. Recent discoveries of feathered dinosaurs in China inspire new thinking on the origin of feathers. In the laboratory, epithelial - mesenchymal recombinations and molecular mis-expressions were carried out to test the plasticity of epithelial organ formation. We review the work on the transformation of scales into feathers, conversion between barbs and rachis and the production of "chicken teeth". In mammals, tilting the balance of the BMP pathway in K14 noggin transgenic mice alters the number, size and phenotypes of different ectodermal organs, making investigators rethink the distinction between morpho-regulation and pathological changes. Models on the evolution of feathers and hairs from reptile integuments are discussed. A hypothetical Evo-Devo space where diverse integument appendages can be placed according to complex phenotypes and novel developmental mechanisms is presented.
关键词	Feather Scale Hair Evolution Development Mesozoic Skin Appendage
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
URL	查看原文
关键词[WOS]	AVIAN SCALE DEVELOPMENT ; BETA BETA KERATINS ; ALLIGATOR ALLIGATOR-MISSISSIPPIENSIS ; FOLLICULAR STEM-CELLS ; HUMAN HAIR-FOLLICLES ; EVOLUTIONARY ORIGIN ; FEATHER MORPHOGENESIS ; MAMMARY-GLAND ; IN-VITRO ; EMBRYONIC-DEVELOPMENT
收录类别	SCI
语种	英语
WOS研究方向	Developmental Biology
WOS类目	Developmental Biology
WOS记录号	WOS:000222225000020
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.205/handle/311034/3687
专题	中科院古脊椎所（2000年以后）
通讯作者	Chuong, CM (reprint author), Univ So Calif, Keck Sch Med, Dept Pathol, HMR 315B,2011 Zonal Ave, Los Angeles, CA 90089 USA.
作者单位	1.Univ So Calif, Keck Sch Med, Dept Pathol, Los Angeles, CA 90089 USA 2.Chinese Acad Sci, Inst Vertebrate Paleontol & Paleoanthropol, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Wu, P,Hou, LH,Plikus, M,et al. Evo-Devo of amniote integuments and appendages[J]. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY,2004,48(2-3):249-270.
APA	Wu, P.,Hou, LH.,Plikus, M.,Hughes, M.,Scehnet, J.,...&Chuong, CM .(2004).Evo-Devo of amniote integuments and appendages.INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY,48(2-3),249-270.
MLA	Wu, P,et al."Evo-Devo of amniote integuments and appendages".INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY 48.2-3(2004):249-270.

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