Genetic history of an archaic hominin group from Denisova Cave in Siberia

IVPP-IR > 中科院古脊椎所（2000年以后）

	Genetic history of an archaic hominin group from Denisova Cave in Siberia
	Reich, David 1,2,3; Green, Richard E.4,5; Kircher, Martin 4; Krause, Johannes 4,6; Patterson, Nick 2,3; Durand, Eric Y.7; Viola, Bence 4,8; Briggs, Adrian W.1,4; Stenzel, Udo 4; Johnson, Philip L. F.9; Maricic, Tomislav 4; Good, Jeffrey M.10; Marques-Bonet, Tomas 11,12; Alkan, Can 11; Fu, Qiaomei 4,13; Mallick, Swapan 1,2,3; Li, Heng 2,3; Meyer, Matthias 4; Eichler, Evan E.11; Stoneking, Mark 4; Richards, Michael 8,14; Talamo, Sahra 8; Shunkov, Michael V.15; Derevianko, Anatoli P.15; Hublin, Jean-Jacques 8; Kelso, Janet 4; Slatkin, Montgomery 7; Paeaebo, Svante 4; reich@genetics.med.harvard.edu ; bence.viola@eva.mpg.de ; paabo@eva.mpg.de
	2010-12-23
发表期刊	NATURE
ISSN	0028-0836
卷号	468 期号:7327 页码:1053-1060
文章类型	Article
摘要	Using DNA extracted from a finger bone found in Denisova Cave in southern Siberia, we have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This individual is from a group that shares a common origin with Neanderthals. This population was not involved in the putative gene flow from Neanderthals into Eurasians; however, the data suggest that it contributed 4-6% of its genetic material to the genomes of present-day Melanesians. We designate this hominin population 'Denisovans' and suggest that it may have been widespread in Asia during the Late Pleistocene epoch. A tooth found in Denisova Cave carries a mitochondrial genome highly similar to that of the finger bone. This tooth shares no derived morphological features with Neanderthals or modern humans, further indicating that Denisovans have an evolutionary history distinct from Neanderthals and modern humans.
关键词	Neanderthal Genome Mitochondrial-dna Mtdna Sequence Diversity Indonesia Patterns Flores Dates Sima
WOS标题词	Science & Technology
URL	查看原文
关键词[WOS]	NEANDERTHAL GENOME ; MITOCHONDRIAL-DNA ; MTDNA SEQUENCE ; DIVERSITY ; INDONESIA ; PATTERNS ; FLORES ; DATES ; SIMA
收录类别	SCI
语种	英语
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000285553800049
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.205/handle/311034/4483
专题	中科院古脊椎所（2000年以后）
通讯作者	reich@genetics.med.harvard.edu; bence.viola@eva.mpg.de; paabo@eva.mpg.de
作者单位	1.Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA 2.MIT, Broad Inst, Cambridge, MA 02142 USA 3.Harvard Univ, Cambridge, MA 02142 USA 4.Max Planck Inst Evolutionary Anthropol, Dept Evolutionary Genet, D-04103 Leipzig, Germany 5.Univ Calif Santa Cruz, Dept Biomol Engn, Santa Cruz, CA 95064 USA 6.Univ Tubingen, Inst Nat Wissensch Archaol, D-72070 Tubingen, Germany 7.Univ Calif Berkeley, Dept Integrat Biol, Berkeley, CA 94720 USA 8.Max Planck Inst Evolutionary Anthropol, Dept Human Evolut, D-04103 Leipzig, Germany 9.Emory Univ, Dept Biol, Atlanta, GA 30322 USA 10.Univ Montana, Div Biol Sci, Missoula, MT 59812 USA 11.Univ Washington, Howard Hughes Med Inst, Dept Genome Sci, Seattle, WA 98195 USA 12.Inst Evolutionary Biol UPF CSIC, Barcelona 08003, Spain 13.Chinese Acad Sci, Inst Vertebrate Paleontol & Paleoanthropol, CAS MPS Joint Lab Human Evolut & Archeometry, Beijing 100044, Peoples R China 14.Univ British Columbia, Dept Anthropol, Vancouver, BC V6T 1Z1, Canada 15.Russian Acad Sci, Inst Archaeol Ethnog, Siberian Branch, Palaeolith Dept, Novosibirsk 630090, Russia
推荐引用方式 GB/T 7714	Reich, David,Green, Richard E.,Kircher, Martin,et al. Genetic history of an archaic hominin group from Denisova Cave in Siberia[J]. NATURE,2010,468(7327):1053-1060.
APA	Reich, David.,Green, Richard E..,Kircher, Martin.,Krause, Johannes.,Patterson, Nick.,...&paabo@eva.mpg.de.(2010).Genetic history of an archaic hominin group from Denisova Cave in Siberia.NATURE,468(7327),1053-1060.
MLA	Reich, David,et al."Genetic history of an archaic hominin group from Denisova Cave in Siberia".NATURE 468.7327(2010):1053-1060.

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