An early modern human from Romania with a recent Neanderthal ancestor

IVPP-IR > 中科院古脊椎所（2000年以后）

	An early modern human from Romania with a recent Neanderthal ancestor
	Fu, Qiaomei 1,2,3; Hajdinjak, Mateja 3; Moldovan, Oana Teodora 4; Constantin, Silviu 5; Mallick, Swapan 2,6,7; Skoglund, Pontus 2; Patterson, Nick 6; Rohland, Nadin 2; Lazaridis, Iosif 2; Nickel, Birgit 3; Viola, Bence 3,7,8; Pruefer, Kay 3; Meyer, Matthias 3; Kelso, Janet 3; Reich, David 2,6,9; Paeaebo, Svante 3
	2015-08-13
发表期刊	NATURE
卷号	524 期号:7564 页码:216-+
文章类型	Article
摘要	Neanderthals are thought to have disappeared in Europe approximately 39,000-41,000 years ago but they have contributed 1-3% of the DNA of present-day people in Eurasia(1). Here we analyse DNA from a 37,000-42,000-year-old(2) modern human from Pestera cu Oase, Romania. Although the specimen contains small amounts of human DNA, we use an enrichment strategy to isolate sites that are informative about its relationship to Neanderthals and present-day humans. We find that on the order of 6-9% of the genome of the Oase individual is derived from Neanderthals, more than any other modern human sequenced to date. Three chromosomal segments of Neanderthal ancestry are over 50 centimorgans in size, indicating that this individual had a Neanderthal ancestor as recently as four to six generations back. However, the Oase individual does not share more alleles with later Europeans than with East Asians, suggesting that the Oase population did not contribute substantially to later humans in Europe.
WOS标题词	Science & Technology
关键词[WOS]	GENOME SEQUENCE ; ANCIENT DNA ; EUROPEANS ; CAVE ; ADMIXTURE ; HISTORY ; POPULATIONS ; ORIGINS ; SIBERIA ; SYSTEMS
收录类别	SCI
语种	英语
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000359386900031
引用统计	被引频次：447[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://119.78.100.205/handle/311034/7483
专题	中科院古脊椎所（2000年以后）
作者单位	1.Chinese Acad Sci, IVPP, Key Lab Vertebrate Evolut & Human Origins, Beijing 100044, Peoples R China 2.Harvard Univ, Dept Genet, Sch Med, Boston, MA 02115 USA 3.Max Planck Inst Evolutionary Anthropol, Dept Evolutionary Genet, D-04103 Leipzig, Germany 4.Emil Racovita Inst Speleol, Cluj Branch, Cluj Napoca 400006, Romania 5.Emil Racovita Inst Speleol, Dept Geospeleol & Paleontol, Bucharest 010986 12, Romania 6.Broad Inst MIT & Harvard, Cambridge, MA 02142 USA 7.Max Planck Inst Evolutionary Anthropol, Dept Human Evolut, D-04103 Leipzig, Germany 8.Univ Toronto, Dept Anthropol, Toronto, ON M5S 2S2, Canada 9.Harvard Univ, Sch Med, Howard Hughes Med Inst, Boston, MA USA
推荐引用方式 GB/T 7714	Fu, Qiaomei,Hajdinjak, Mateja,Moldovan, Oana Teodora,et al. An early modern human from Romania with a recent Neanderthal ancestor[J]. NATURE,2015,524(7564):216-+.
APA	Fu, Qiaomei.,Hajdinjak, Mateja.,Moldovan, Oana Teodora.,Constantin, Silviu.,Mallick, Swapan.,...&Paeaebo, Svante.(2015).An early modern human from Romania with a recent Neanderthal ancestor.NATURE,524(7564),216-+.
MLA	Fu, Qiaomei,et al."An early modern human from Romania with a recent Neanderthal ancestor".NATURE 524.7564(2015):216-+.

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