Bronze Age cheese reveals human-<i>Lactobacillus</i> interactions over evolutionary history

doi:10.1016/j.cell.2024.08.008

IVPP-IR

	*Bronze Age cheese reveals human-Lactobacillus* interactions over evolutionary history**
	Liu, Yichen 1,2; Miao, Bo 1; Li, Wenying 3; Hu, Xingjun 4; Bai, Fan 1,2; Abuduresule, Yidilisi 3; Liu, Yalin 1,2; Zheng, Zequan 1,2; Wang, Wenjun 1,5; Chen, Zehui 1,2; Zhu, Shilun 1,2; Feng, Xiaotian 1; Cao, Peng 1; Ping, Wanjing 1; Yang, Ruowei 1; Dai, Qingyan 1; Liu, Feng 1; Tian, Chan 6; Yang, Yimin 7; Fu, Qiaomei1,2
	2024-10-17
发表期刊	CELL
ISSN	0092-8674
卷号	187 期号:21 页码:5891-+
通讯作者	Yang, Yimin(yiminyang@ucas.ac.cn) ; Fu, Qiaomei(fuqiaomei@ivpp.ac.cn)
摘要	Despite the long history of consumption of fermented dairy, little is known about how the fermented microbes were utilized and evolved over human history. Here, by retrieving ancient DNA of Bronze Age kefir cheese (similar to 3,500 years ago) from the Xiaohe cemetery, we explored past human-microbial interactions. Although it was previously suggested that kefir was spread from the Northern Caucasus to Europe and other regions, we found an additional spreading route of kefir from Xinjiang to inland East Asia. Over evolutionary history, the East Asian strains gained multiple gene clusters with defensive roles against environmental stressors, which can be a result of the adaptation of Lactobacillus strains to various environmental niches and human selection. Overall, our results highlight the role of past human activities in shaping the evolution of human-related microbes, and such insights can, in turn, provide a better understanding of past human behaviors.
DOI	10.1016/j.cell.2024.08.008
关键词[WOS]	ANCIENT ; PRODUCTS ; BACTERIA ; FOODS ; KEFIR ; CAVE ; MILK ; TOOL
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[41925009] ; National Natural Science Foundation of China[42302021] ; Chinese Academy of Sciences (CAS)[YSBR-019] ; Chinese Academy of Sciences (CAS)[2023000065] ; Feng Foundation of Biomedical Research ; Fundamental Research Funds for the Central Universities
项目资助者	National Natural Science Foundation of China ; Chinese Academy of Sciences (CAS) ; Feng Foundation of Biomedical Research ; Fundamental Research Funds for the Central Universities
WOS研究方向	Biochemistry & Molecular Biology ; Cell Biology
WOS类目	Biochemistry & Molecular Biology ; Cell Biology
WOS记录号	WOS:001389449400001
出版者	CELL PRESS
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.205/handle/311034/24252
专题	中国科学院古脊椎动物与古人类研究所
通讯作者	Yang, Yimin; Fu, Qiaomei
作者单位	1.Chinese Acad Sci, Inst Vertebrate Paleontol & Paleoanthropol, Key Lab Vertebrate Evolut & Human Origins, Beijing 100035, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Xinjiang Cultural Rel & Archaeol Inst, Urumqi 830000, Peoples R China 4.Xinjiang Univ, Sch Hist, Res Ctr Governance Chinas Northwest Frontier Hist, Udumqi 830046, Peoples R China 5.Natl Ctr Archaeol, Sci & Technol Archaeol, Beijing 100013, Peoples R China 6.Peking Univ Third Hosp, Dept Obstet & Gynecol, Ctr Reprod Med, Beijing 100191, Peoples R China 7.Univ Chinese Acad Sci, Dept Archaeol & Anthropol, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Liu, Yichen,Miao, Bo,Li, Wenying,et al. Bronze Age cheese reveals human-Lactobacillus interactions over evolutionary history[J]. CELL,2024,187(21):5891-+.
APA	Liu, Yichen.,Miao, Bo.,Li, Wenying.,Hu, Xingjun.,Bai, Fan.,...&Fu, Qiaomei.(2024).Bronze Age cheese reveals human-Lactobacillus interactions over evolutionary history.CELL,187(21),5891-+.
MLA	Liu, Yichen,et al."Bronze Age cheese reveals human-Lactobacillus interactions over evolutionary history".CELL 187.21(2024):5891-+.