Convergent functional evolution of mRNA-binding proteins fuels allotetraploid adaptation in cyprinids

doi:10.1016/j.celrep.2025.116635

IVPP-IR

	Convergent functional evolution of mRNA-binding proteins fuels allotetraploid adaptation in cyprinids
	Liu, Fujiang 1; Wu, Jiahong 2; Dong, Yichen 1; Song, Yue 3,5; Tong, Baichuan 1; Peng, Yicheng 1; He, Liyan 1; Xu, Luohao 2; Fan, Guangyi 3; Wu, Feixiang4 ; Wang, Bo 1; Qu, Qingming 1
	2025-12-23
发表期刊	CELL REPORTS
ISSN	2639-1856
卷号	44 期号:12 页码:25
通讯作者	Fan, Guangyi(fanguangyi@genomics.cn) ; Wu, Feixiang(wufeixiang@ivpp.ac.cn) ; Wang, Bo(bowang@xmu.edu.cn) ; Qu, Qingming(quqingming@xmu.edu.cn)
摘要	Polyploidy, the duplication of the entire genome, is a major force in vertebrate evolution, yet how new polyploid species survive and prosper remains unclear. Here, we present a chromosome-level genome of the cyprinid Spinibarbus caldwelli, whose allotetraploid event is dated to similar to 4 million years ago based on transposable element distributions in its two subgenomes. Genomic analyses reveal unique patterns of homoeologous exchanges between the two subgenomes, indicating a gradual evolutionary process prior to their suppression. Furthermore, we identify a striking pattern of accelerated evolution of RNA-binding proteins across independently evolved tetraploid cyprinids. Functional assays of one such protein, Tia1, demonstrate that the tetraploid orthologs may be more efficient at stress granule disassembly than those of diploid relatives. These findings suggest that improved cellular stress management, particularly in RNA processing, might be a key adaptation that has enabled the evolutionary success of polyploid cyprinids.
DOI	10.1016/j.celrep.2025.116635
关键词[WOS]	GENOME PROVIDES INSIGHTS ; PHYLOGENETIC ANALYSIS ; ALIGNMENT ; TRANSCRIPTOME ; RECOMBINATION ; SEQUENCE ; PARALLEL ; TOOL ; CONSEQUENCES ; MECHANISMS
收录类别	SCI
语种	英语
资助项目	Natural Science Foundation of Xiamen[3502Z202473009]###3557 ; Xiamen University###3558 ; National Natural Science Foundation of China[42272013]###3303
项目资助者	Natural Science Foundation of Xiamen ; Xiamen University ; National Natural Science Foundation of China
WOS研究方向	Cell Biology
WOS类目	Cell Biology
WOS记录号	WOS:001630346300006
出版者	CELL PRESS
引用统计
文献类型	期刊论文
条目标识符	http://119.78.100.205/handle/311034/25119
专题	中国科学院古脊椎动物与古人类研究所
通讯作者	Fan, Guangyi; Wu, Feixiang; Wang, Bo; Qu, Qingming
作者单位	1.Xiamen Univ, Fac Med & Life Sci, Sch Life Sci, State Key Lab Cellular Stress Biol, Xiamen 361102, Peoples R China 2.Southwest Univ, Integrat Sci Ctr Germplasm Creat Western China Cho, Key Lab Freshwater Fish Reprod & Dev, Minist Educ,Sch Life Sci, Chongqing 400715, Peoples R China 3.BGI Res, Qingdao 266555, Peoples R China 4.Chinese Acad Sci, Key Lab Vertebrate Evolut & Human Origins, Inst Vertebrate Paleontol & Paleoanthropol, Beijing 100044, Peoples R China 5.Univ Copenhagen, Dept Biol, Lab Integrat Biomed, Univ Pk 13, DK-2100 Copenhagen, Denmark
推荐引用方式 GB/T 7714	Liu, Fujiang,Wu, Jiahong,Dong, Yichen,et al. Convergent functional evolution of mRNA-binding proteins fuels allotetraploid adaptation in cyprinids[J]. CELL REPORTS,2025,44(12):25.
APA	Liu, Fujiang.,Wu, Jiahong.,Dong, Yichen.,Song, Yue.,Tong, Baichuan.,...&Qu, Qingming.(2025).Convergent functional evolution of mRNA-binding proteins fuels allotetraploid adaptation in cyprinids.CELL REPORTS,44(12),25.
MLA	Liu, Fujiang,et al."Convergent functional evolution of mRNA-binding proteins fuels allotetraploid adaptation in cyprinids".CELL REPORTS 44.12(2025):25.