| DNA analysis of an early modern human from Tianyuan Cave, China | |
| Fu, Qiaomei1,2; Meyer, Matthias2; Gao, Xing1; Stenzel, Udo2; Burbano, Hernan A.2,3; Kelso, Janet2; Paeaebo, Svante1,2; qiaomei_fu@eva.mpg.de | |
| 2013-02-05 | |
| 发表期刊 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
 |
| ISSN | 0027-8424 |
| 卷号 | 110期号:6页码:2223-2227 |
| 文章类型 | Article |
| 摘要 | Hominins with morphology similar to present-day humans appear in the fossil record across Eurasia between 40,000 and 50,000 y ago. The genetic relationships between these early modern humans and present-day human populations have not been established. We have extracted DNA from a 40,000-y-old anatomically modern human from Tianyuan Cave outside Beijing, China. Using a highly scalable hybridization enrichment strategy, we determined the DNA sequences of the mitochondrial genome, the entire nonrepetitive portion of chromosome 21 (similar to 30 Mbp), and over 3,000 polymorphic sites across the nuclear genome of this individual. The nuclear DNA sequences determined from this early modern human reveal that the Tianyuan individual derived from a population that was ancestral to many present-day Asians and Native Americans but postdated the divergence of Asians from Europeans. They also show that this individual carried proportions of DNA variants derived from archaic humans similar to present-day people in mainland Asia. |
| 关键词 | Ancient Dna Human Evolution Nuclear Capture Strategy Paleogenetics |
| WOS标题词 | Science & Technology |
| URL | 查看原文 |
| 关键词[WOS] | HUMAN GENETIC HISTORY ; NEANDERTHAL GENOME ; MITOCHONDRIAL-DNA ; SOUTHEAST-ASIA ; EAST-ASIA ; SEQUENCE ; ANCIENT ; ADMIXTURE ; ORIGINS |
| 收录类别 | SCI ; AHCI |
| 语种 | 英语 |
| WOS研究方向 | Science & Technology - Other Topics |
| WOS类目 | Multidisciplinary Sciences |
| WOS记录号 | WOS:000315209800057 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://119.78.100.205/handle/311034/4215 |
| 专题 | 古人类及旧石器研究室 |
| 通讯作者 | qiaomei_fu@eva.mpg.de |
| 作者单位 | 1.Chinese Acad Sci, Inst Vertebrate Paleontol & Paleoanthropol, Max Planck Soc, Joint Lab Human Evolut, Beijing 100044, Peoples R China 2.Max Planck Inst Evolutionary Anthropol, Dept Evolutionary Genet, D-04103 Leipzig, Germany 3.Max Planck Inst Dev Biol, Dept Mol Biol, D-72076 Tubingen, Germany |
| 推荐引用方式 GB/T 7714 | Fu, Qiaomei,Meyer, Matthias,Gao, Xing,et al. DNA analysis of an early modern human from Tianyuan Cave, China[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2013,110(6):2223-2227. |
| APA | Fu, Qiaomei.,Meyer, Matthias.,Gao, Xing.,Stenzel, Udo.,Burbano, Hernan A..,...&qiaomei_fu@eva.mpg.de.(2013).DNA analysis of an early modern human from Tianyuan Cave, China.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,110(6),2223-2227. |
| MLA | Fu, Qiaomei,et al."DNA analysis of an early modern human from Tianyuan Cave, China".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110.6(2013):2223-2227. |
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| DNA田园洞人l.pdf（398KB） | 开放获取 | -- | 浏览 下载 | |||
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